Our customer service:
Validation and monitoring of strain purity
Molecular quality assurance and studies on the genetic stability of strains
Documentation of the genetic stability of strains using molecular fingerprint techniques [read more ...}
Our customers provide:
Organic samples (strains) or the extracted DNA
How can we "measure the genetic stability" of strains?
This is a difficult task. Is there a method on hand which can prove that
genetic changes did not occure to a cell line during a certain treatment?
And this free of doubt? The answer is NO!
However, there are methods available which can be used to verify the identity
of a cell line or strain.
So these methods can be used to prove whether you are dealing with the same
strain over the years or whether there have been genetic changes in the
population which could be due to contaminations.
Keywords: DNA extraction, PCR, AFLP fingerprints, bin, superbin, hyperbin, 01 matrix